In many patients, the disease caused by the H5N1 virus follows an unusually aggressive clinical course, where the patient goes down-hill rapidly.

Initial symptoms include:

• high fever (usually higher than 38°C)
• flu-like symptoms

And possibly:

• diarrhoea
• vomiting
• abdominal pain
• chest pain
• bleeding from the nose and gums.

Almost all patients eventually develop pneumonia and many of their organs may dysfunction.

There may be more symptoms and not all patients have presented with the symptoms above.

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